377 Propionibacterium acnes CAMP factor 1 recognized Toll-Like Receptor-2

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TLR-2 Recognizes Propionibacterium acnes CAMP Factor 1 from Highly Inflammatory Strains

BACKGROUND Propionibacterium acnes (P. acnes) is an anaerobic, Gram-positive bacteria encountered in inflammatory acne lesions, particularly in the pilosebaceous follicle. P. acnes triggers a strong immune response involving keratinocytes, sebocytes and monocytes, the target cells during acne development. Lipoteicoic acid and peptidoglycan induce the inflammatory reaction, but no P. acnes surfa...

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The Opportunistic Pathogen Propionibacterium acnes: Insights into Typing, Human Disease, Clonal Diversification and CAMP Factor Evolution

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2017

ISSN: 0022-202X

DOI: 10.1016/j.jid.2017.07.572